Polymeric nanocarriers as stimuli-responsive systems for targeted tumor (cancer) therapy: Recent advances in drug delivery

Recent Advances of Multi-Stimuli-Responsive Drug Delivery Systems for Cancer Therapy

Nowadays, cancer with an increasing morbidity at an alarming rate is still a major cause of death worldwide [1]. And the most common cancer treatment method is conventional chemotherapy which is based on highly potent anticancer drugs. However, the harmful side-effects due to the nonspecific uptake by normal tissues/organs limit their further applications [2]. To conquer these limitations, an e...

Recent Advances in Stimuli-responsive Poly(amidoamine) Dendrimer Nanocarriers for Drug Delivery

Polyamidoamine (PAMAM) dendrimers have gained so much attention for drug and gene delivery since they have been introduced decades ago. The internal cavities and multivalent surface groups of PAMAM dendrimers have been widely used for small-molecule drugs/biomacromolecules encapsulation and conjugation. The involvement of PAMAM dendrimers in drug delivery systems (DDSs) has significantly improv...

Recent Advances in Stimuli-Responsive Release Function Drug Delivery Systems for Tumor Treatment.

Benefiting from the development of nanotechnology, drug delivery systems (DDSs) with stimuli-responsive controlled release function show great potential in clinical anti-tumor applications. By using a DDS, the harsh side effects of traditional anti-cancer drug treatments and damage to normal tissues and organs can be avoided to the greatest extent. An ideal DDS must firstly meet bio-safety stan...

Advances in Targeted Drug Delivery

Advances in Targeted Drug Delivery